Enoteca L'Antidoto
A charming Trastevere wine bar perfect for bottles of natural wine paired with thoughtful small plates.

Tucked away in the winding streets of Trastevere, Enoteca L’Antidoto is the kind of neighborhood gem that makes you feel like you’ve discovered something special. This intimate wine bar trades the typical by-the-glass approach for a bottle-only policy, which turns out to be more of an invitation than a restriction. It’s the perfect excuse to linger longer and explore their carefully curated selection of mostly natural wines from across Italy and beyond.
The food here is designed to complement rather than compete with the wine. Think lighter fare that lets the bottles shine while still satisfying your appetite. The flatbread arrives topped with tangy yogurt and whatever vegetables happen to be at their freshest, while the tuna crudo gets an unexpected kick from a spicy caponata that somehow works beautifully. Nearly everything on the rotating menu comes from local producers in the surrounding Lazio region, giving the whole experience a sense of place that feels genuinely Roman.
Don’t skip dessert, even if you think you’re too full. The plum sorbet—crowned with buttery roasted hazelnuts, almonds, and aromatic fennel seeds—is the kind of finish that stays with you long after you’ve left. It’s simple and elegant, much like the restaurant itself.
Enoteca L’Antidoto is ideal for those evenings when you want something more than aperitivo but less than a full-blown dinner. Grab a seat at the bar, order a juicy Tuscan Trebbiano, and let the night unfold naturally. This is Trastevere at its best—unhurried, unpretentious, and utterly delicious.
Enoteca L'Antidoto
Wine Bar • $$
Location
Vicolo del Bologna, 19Trastevere
Rome, Italy
Links
Perfect For
Must Try
- Flatbread with Yogurt and Seasonal VegetablesA delicate flatbread topped with creamy yogurt and whatever vegetables are at their peak
- Tuna Crudo with CaponataFresh raw tuna paired with a spicy Sicilian caponata
- Plum Sorbet with Roasted NutsSeasonal plum sorbet finished with buttery hazelnuts, almonds, and fragrant fennel seeds
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